Explanation: Business risk has the greatest impact on the design of an IT governance framework, as it determines the level of control, oversight, and alignment that is required for the IT function to support the business objectives and mitigate the potential threats and vulnerabilities. Business risk is influenced by various factors, such as the industry, market, customer, competitor, regulatory, and environmental context of the enterprise. Therefore, the IT governance framework should be tailored to suit the specific risk profile and appetite of the enterprise, and to address the key risk areas and scenarios that could affect the business performance and value. According to COBIT 2019, one of the design factors that can influence the design of an enterprise’s governance system is the risk profile1. This design factor reflects the degree of risk exposure and tolerance that the enterprise has in relation to its use of information and technology1. The risk profile can be assessed by considering various aspects, such as the likelihood and impact of risk events, the sources and types of risks, the risk appetite and thresholds, the risk management capabilities and maturity, and the risk culture and awareness1. Based on the risk profile, the enterprise can decide on the appropriate governance objectives, components, enablers, practices, and activities that are needed to manage and mitigate the risks effectively1. The other options, IT performance metrics, resource allocation, and business leadership, are also important for the design of an IT governance framework, but they are not as impactful as business risk. IT performance metrics are used to measure and monitor the effectiveness and efficiency of the IT function in delivering value to the business2. Resource allocation is a process that optimizes the use of IT resources across multiple programs and projects in alignment with the business goals and priorities3. Business leadership is a role that provides strategic direction, guidance, and support for the IT function in achieving its objectives4. However, these factors are more related to the implementation and execution of the IT governance framework, rather than its design. They are also influenced by the business risk factor, as they depend on the level of risk exposure and tolerance that the enterprise has. References := IT Governance: Definitions, Frameworks and Planning - ProjectManager, Resource Allocation Done Right: Best Practices for 2022 & Beyond, The Role of Business Leadership in Effective IT Governance, COBIT Design Factors: A Dynamic Approach to Tailoring Governance in … - ISACA